The molecular basis of innate immunity in the horseshoe crab

被引：198

作者：

Iwanaga, S ^{[1
]}

机构：

[1] Chemoserotherapeut Res Inst, Kumamoto 8608568, Japan

来源：

CURRENT OPINION IN IMMUNOLOGY | 2002年 / 14卷 / 01期

关键词：

D O I：

10.1016/S0952-7915(01)00302-8

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

During the past two decades, the molecular structures and functions have been established for various defense molecules, using horseshoe crab (limulus) as a model animal. These defense molecules include clotting factors, proteinase inhibitors, lectins, antimicrobial peptides and other humoral factors found mainly in the hemolymph. These components of the cellular and humoral systems, which together comprise innate immunity, defend horseshoe crab effectively from invading microbes.

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页码：87 / 95

页数：9

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