Inhibition of tumour growth and inflammation by consumption of tea

被引：26

作者：

Das, M ^{[1
]}

Sur, P ^{[1
]}

Gomes, A ^{[1
]}

Vedasiromoni, JR ^{[1
]}

Ganguly, DK ^{[1
]}

机构：

[1] Indian Inst Chem Biol, Div Pharmacol & Expt Therapeut, Kolkata 700032, W Bengal, India

来源：

PHYTOTHERAPY RESEARCH | 2002年 / 16卷

关键词：

Camellia sinensis var assamica (Theaceae); solid tumour; antitumour activity; antiinflammatory activity; 3-methylcholanthrene (3-MC); tea extract;

D O I：

10.1002/ptr.797

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The antitumour effect of tea was evaluated in the 3-methylcholanthrene (3-MC) induced solid tumour model in mice. Both black and green tea inhibited tumour growth and prevented metastasis. Histopathological study showed that tea treatment was able to reduce malignancy. Superoxide dismutase (SOD), a free radical scavenger, was found to be significantly increased in the serum of mice administered tea. Moreover, tea extracts were able to reduce the level of thiobarbituric acid reactive substance (TBARS) in the sera of mice. Tea extracts (both black and green) also showed antiinflammatory activity in the carrageenan-induced paw oedema model in the rat. Copyright (C) 2002 John Wiley Sons, Ltd.

引用

页码：S40 / S44

页数：5

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