Globus pallidus deep brain stimulation in dystonia

被引:52
作者
Diamond, Alan
Shahed, Joohi
Azher, Shaheda
Dat-Vuong, Kevin
Jankovic, Joseph
机构
[1] Baylor Coll Med, Dept Neurol, Parkinsons Dis Ctr, Houston, TX 77030 USA
[2] Baylor Coll Med, Dept Neurol, Movement Disorders Clin, Houston, TX 77030 USA
关键词
D O I
10.1002/mds.20767
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Globus pallidus deep brain stimulation (GPi-DBS) is a useful alternative in the treatment of dystonia. Patients selected for GPi-DBS were prospectively rated with the Unified Dystonia Rating Scale (UDRS). Also, "blinded" videotape assessments were performed. Eleven patients were identified. Compared with pre-DBS scores, there were improvements in mean total UDRS score (15.3%) and in the following subscores: neck (18.18%), trunk (32.9%), arm(17.9%), and leg (19.9%). One patient developed a skin infection and erosion requiring surgical debridement. GPi-DBS is a safe and effective treatment for generalized dystonia in patients who remained impaired, despite optimal medical therapy. (C) 2006 Movement Disorder Society.
引用
收藏
页码:692 / 695
页数:4
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