In silico patent searching reveals a new cannabinoid receptor

被引:248
作者
Baker, D
Pryce, G
Davies, WL
Hiley, CR
机构
[1] UCL, Inst Neurol, Dept Neuroinflammat, London WC1N 1PJ, England
[2] Univ Cambridge, Dept Pharmacol, Cambridge CB2 1PD, England
关键词
D O I
10.1016/j.tips.2005.11.003
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Increasing evidence suggests that some cannabinoids mediate their effects independently of the known cannabinoid CB1 and CB2 receptors. Two recently published patents indicate that several cannabinoid receptor ligands also bind to the orphan G-protein-coupled receptor GPR55. This receptor is reported to be expressed in several tissues and might function in lipid or vascular biology. Thus, GPR55 might represent a new cannabinoid receptor.
引用
收藏
页码:1 / 4
页数:4
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