Development of microfluidic channels for the culture of mammalian embryos

被引：8

作者：

Davis, JA ^{[1
]}

Raty, S ^{[1
]}

Eddington, DT ^{[1
]}

Glasgow, IK ^{[1
]}

Zeringue, HC ^{[1
]}

Wheeler, MB ^{[1
]}

Beebe, DJ ^{[1
]}

机构：

[1] Princeton Univ, Dept Elect Engn, Princeton, NJ 08544 USA

来源：

1ST ANNUAL INTERNATIONAL IEEE-EMBS SPECIAL TOPIC CONFERENCE ON MICROTECHNOLOGIES IN MEDICINE & BIOLOGY, PROCEEDINGS | 2000年

关键词：

D O I：

10.1109/MMB.2000.893793

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Microfluidic channels are explored as a tool for the culture of mammalian embryos. Three different materials are used to construct microfluidic devices for embyro culture: silicon, glass, and polydimethylsiloxane. Practical issues including, loading, localization-visualization and retrieval of the embryos in the microchannels, bubble formation within the device, and development of cleaning and sterilization procedures are discussed and addressed via design iterations. Preliminary data on embryo development within the microchannels have been collected.

引用

页码：307 / 310

页数：4

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