Frailty is associated with postoperative complications in older adults with medical problems

被引:333
作者
Dasgupta, Monidipa [1 ]
Rolfson, Darryl B. [2 ]
Stolee, Paul [3 ,4 ,5 ]
Borrie, Michael J. [6 ]
Speechley, Mark [5 ,7 ]
机构
[1] Univ Western Ontario, St Josephs Healthcare Ctr, Schulich Sch Med, Dept Med,Div Geriatr Med, London, ON N6A 4V2, Canada
[2] Univ Alberta, Glenrose Rehabil Hosp, Dept Med, Div Geriatr Med, Edmonton, AB T5G 0B7, Canada
[3] Univ Waterloo, Sch Optometry, Waterloo, ON N2L 3G1, Canada
[4] Univ Waterloo, Dept Hlth Studies & Gerontol, Waterloo, ON N2L 3G1, Canada
[5] Univ Western Ontario, Schulich Sch Med, Dept Epidemiol & Biostat, London, ON N6A 3K7, Canada
[6] Univ Western Ontario, St Josephs Healthcare Ctr, Schulich Sch Med,Div Geriatr Med, Parkwood Hosp,Dept Med, London, ON N6C 5J1, Canada
[7] Univ Western Ontario, Dept Epidemiol & Biostat, Schulich Sch Med, London, ON N6A 5C1, Canada
关键词
Preoperative care; Postoperative complications; Frailty; Co-morbidity; MULTIFACTORIAL RISK INDEX; THORACIC-SURGERY; PREDICTION; VALIDATION; DELIRIUM; DISEASE; PEOPLE; AGE;
D O I
10.1016/j.archger.2007.10.007
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
030301 [社会学]; 100201 [内科学];
摘要
We sought to test whether frailty may be predictive of operative risk in older adults with medical problems. One hundred and twenty-five patients at least 70 years of age had a previously developed frailty screen, the Edmonton Frail Scale (EFS), administered at a pre-surgical clinic, prior to elective non-cardiac surgery. A blinded chart audit assessed for postoperative medical complications, length of stay and inability to be discharged home. The mean age of patients was 77 (range 70-92) and most (82%) underwent orthopedic procedures. Increasing frailty was associated with postoperative complications (p = 0.02), increased length of hospitalization (p = 0.004) and inability to be discharged home (p = 0.01), independent of age. EFS scores of 3 or less were associated with a lower risk of having a complication (age-adjusted OR 0.27, 95% Cl 0.09-0.80, likelihood ratio of 0.33) and a higher chance (80%) of being discharged home (p < 0.02). EFS scores exceeding 7 were associated with increased complications (OR 5.02, 95% Cl 1.55-16.25, likelihood ratio of 3.9) and a lower chance of being discharged home (40%, p < 0.02). This study suggests that a frailty screen can refine risk estimates of postoperative complications in older adults undergoing elective non-cardiac surgery. (C) 2007 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:78 / 83
页数:6
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