New ideas about atrial fibrillation 50 years on

被引：1160

作者：

Nattel, S ^{[1
]}

机构：

[1] Montreal Heart Inst, Dept Med, Res Ctr, Montreal, PQ H1T 1C8, Canada

[2] Univ Montreal, Montreal, PQ, Canada

来源：

NATURE | 2002年 / 415卷 / 6868期

关键词：

D O I：

10.1038/415219a

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Atrial fibrillation is a condition in which control of heart rhythm is taken away from the normal sinus node pacemaker by rapid activity in different areas within the upper chambers (atria) of the heart. This results in rapid and irregular atrial activity and, instead of contracting, the atria only quiver. It is the most common cardiac rhythm disturbance and contributes substantially to cardiac morbidity and mortality. For over 50 years, the prevailing model of atrial fibrillation involved multiple simultaneous re-entrant waves, but in light of new discoveries this hypothesis is now undergoing re-evaluation.

引用

页码：219 / 226

页数：8

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