Nonpeptidic inhibitors of recombinant human calpain I

被引：4

作者：

Chatterjee, S

Senadhi, S

BozyczkoCoyne, D

Siman, R

Mallamo, JP

机构：

[1] Department of Chemistry, West Chester, PA 19380

[2] Dept. of Biochemistry Cephalon, Inc., West Chester, PA 19380

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1997年 / 7卷 / 03期

关键词：

D O I：

10.1016/S0960-894X(97)00003-6

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：287 / 290

页数：4

共 16 条

[1] INACTIVATION OF CALPAIN BY PEPTIDYL FLUOROMETHYL KETONES [J].

ANGLIKER, H ;

ANAGLI, J ;

SHAW, E .

JOURNAL OF MEDICINAL CHEMISTRY, 1992, 35 (02) :216-220

[2]

Barinaga M, 1996, SCIENCE, V272, P664

[3] Xanthene derived potent nonpeptidic inhibitors of recombinant human calpain I [J].

Chaterjee, S ;

Iqbal, M ;

Kauer, JC ;

Mallamo, JP ;

Senadhi, S ;

Mallya, S ;

BozyczkoCoyne, D ;

Siman, R .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1996, 6 (13) :1619-1622

[4] Potent fluoromethyl ketone inhibitors of recombinant human calpain I+ [J].

Chatterjee, S ;

Josef, K ;

Wells, G ;

Iqbal, M ;

Bihovsky, R ;

Mallamo, JP ;

Ator, MA ;

BozyczkoCoyne, D ;

Mallya, S ;

Senadhi, S ;

Siman, R .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1996, 6 (11) :1237-1240

[5] THE DESIGN OF PEPTIDYLDIAZOMETHANE INHIBITORS TO DISTINGUISH BETWEEN THE CYSTEINE PROTEINASES CALPAIN-II, CATHEPSIN-L AND CATHEPSIN-B [J].

CRAWFORD, C ;

MASON, RW ;

WIKSTROM, P ;

SHAW, E .

BIOCHEMICAL JOURNAL, 1988, 253 (03) :751-758

[6] CALCIUM-ACTIVATED NEUTRAL PROTEASE (CALPAIN) SYSTEM - STRUCTURE, FUNCTION, AND REGULATION [J].

CROALL, DE ;

DEMARTINO, GN .

PHYSIOLOGICAL REVIEWS, 1991, 71 (03) :813-847

[7] APPLICATIONS OF OXAZIRIDINES IN ORGANIC-SYNTHESIS [J].

DAVIS, FA ;

SHEPPARD, AC .

TETRAHEDRON, 1989, 45 (18) :5703-5742

[8] STEREOSPECIFIC SYNTHESIS OF PEPTIDYL ALPHA-KETO AMIDES AS INHIBITORS OF CALPAIN [J].

HARBESON, SL ;

ABELLEIRA, SM ;

AKIYAMA, A ;

BARRETT, R ;

CARROLL, RM ;

STRAUB, JA ;

TKACZ, JN ;

WU, CC ;

MUSSO, GF .

JOURNAL OF MEDICINAL CHEMISTRY, 1994, 37 (18) :2918-2929

[9] CHARACTERIZATION OF A CONTINUOUS FLUOROGENIC ASSAY FOR CALPAIN-I - KINETIC EVALUATION OF PEPTIDE ALDEHYDES, HALOMETHYL KETONES AND (ACYLOXY)METHYL KETONES AS INHIBITORS OF THE ENZYME [J].

HARRIS, AL ;

GREGORY, JS ;

MAYCOCK, AL ;

GRAYBILL, TL ;

OSIFO, IK ;

SCHMIDT, SJ ;

DOLLE, RE .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1995, 5 (04) :393-398

[10] ESTER AND AMIDE DERIVATIVES OF E64C AS INHIBITORS OF PLATELET CALPAINS [J].

HUANG, ZY ;

MCGOWAN, EB ;

DETWILER, TC .

JOURNAL OF MEDICINAL CHEMISTRY, 1992, 35 (11) :2048-2054

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