Transcription factories

被引：56

作者：

Carter, David R. F. ^{[2
]}

Eskiw, Christopher ^{[3
]}

Cook, Peter R. ^{[1
]}

机构：

[1] Univ Oxford, Sir William Dunn Sch Pathol, Oxford OX1 3RE, England

[2] Cranfield Univ, Cranfield MK43 0AL, Beds, England

[3] Babraham Inst, Lab Chromatin & Gene Express, Cambridge CB22 3AT, England

来源：

BIOCHEMICAL SOCIETY TRANSACTIONS | 2008年 / 36卷

基金：

英国惠康基金; 英国生物技术与生命科学研究理事会;

关键词：

chromosome conformation capture (3C); chromosome organization; genome organization; locus control region; transcription factory;

D O I：

10.1042/BST0360585

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

There is increasing evidence that different transcription units are transcribed together in discrete nuclear structures known as transcription factories. Various new techniques enable us to detect and characterize these structures. We review the latest findings and discuss how they support a model for transcription and chromosome organization.

引用

页码：585 / 589

页数：5

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