Aquaporins in the hepatobiliary system

被引：52

作者：

Masyuk, AI ^{[1
]}

LaRusso, NF ^{[1
]}

机构：

[1] Mayo Clin Coll Med, Rochester, MN 55905 USA

来源：

HEPATOLOGY | 2006年 / 43卷 / 02期

关键词：

D O I：

10.1002/hep.20996

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The review focuses on the potential physiological and pathophysiological roles of aquaporins (AQPs), a family of water channel proteins, in the hepatobiliary system. Among 13 aquaporins (AQPO-AQP12) cloned in mammals, seven AQPs have been identified in the liver and biliary tree. Accumulating evidence suggests that AQPs are likely involved in canalicular and ductal bile secretion, gluconeogenesis and microbial infection and may have other novel roles that affect liver function.

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收藏

页码：S75 / S81

页数：7

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