Contralateral and ipsilateral motor effects after transcranial direct current stimulation

被引:137
作者
Vines, Bradley W.
Nair, Dinesh G.
Schlaug, Gottfried
机构
[1] Beth Israel Deaconess Med Ctr, Dept Neurol, Neuroimaging Lab, Boston, MA 02215 USA
[2] Harvard Univ, Sch Med, Boston, MA 02115 USA
关键词
finger sequence; interhemispheric inhibition; M1; primary motor cortex; motor recovery; tDCS; transcranial direct current stimulation;
D O I
10.1097/00001756-200604240-00023
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Transcranial direct current stimulation over the left motor area influenced both contralateral and ipsilateral finger sequence movements in seven healthy adults. Effects for the two hands were reversed: anodal stimulation improved right-hand performance significantly more than cathodal stimulation, whereas cathodal stimulation improved left-hand performance significantly more than anodal stimulation. The results show that stimulating a motor region directly, or indirectly by modulating activity in the homologous region on the opposite hemisphere, can affect motor skill acquisition, presumably by facilitating effective synaptic connectivity. This outcome provides evidence for the role of interhemispheric inhibition in corticomotor functioning, and also has implications for treatment methods aimed at facilitating motor recovery after stroke.
引用
收藏
页码:671 / 674
页数:4
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