Coordinated polar localization of auxin efflux carrier PIN1 by GNOM ARF GEF

被引：575

作者：

Steinmann, T

Geldner, N

Grebe, M

Mangold, S

Jackson, CL

Paris, S

Gälweiler, L

Palme, K

Jürgens, G

机构：

[1] Univ Tubingen, Zentrum Mol Biol Pflanzen, D-72076 Tubingen, Germany

[2] CEA Saclay, Serv Biochim & Genet Mol, F-91191 Gif Sur Yvette, France

[3] CNRS, Inst Pharmacol Mol & Cellulaire, F-06560 Valbonne, France

[4] Max Planck Gesell, Max Delbruck Lab, D-50829 Cologne, Germany

来源：

SCIENCE | 1999年 / 286卷 / 5438期

关键词：

D O I：

10.1126/science.286.5438.316

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The plant hormone auxin is transported in a polar manner along the shoot-root axis, which requires efflux carriers such as PIN1. Asymmetric localization-of PIN1 develops from a random distribution in Arabidopsis early embryogenesis. Coordinated polar localization of PIN1 is defective in gnom embryos. GNOM is a membrane-associated guanine-nucleotide exchange factor on ADP-ribosylation factor G protein (ARF GEF). Thus, GNOM-dependent vesicle trafficking may establish cell polarity, resulting in polar auxin transport.

引用

页码：316 / 318

页数：3

共 22 条

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