Gout: why is this curable disease so seldom cured?

被引:235
作者
Doherty, Michael [1 ]
Jansen, Tim L. [2 ]
Nuki, George [3 ]
Pascual, Eliseo [4 ,5 ]
Perez-Ruiz, Fernando [6 ]
Punzi, Leonardo [7 ]
So, Alexander K. [8 ]
Bardin, Thomas [9 ]
机构
[1] City Hosp, Dept Rheumatol, Nottingham NG5 1PB, England
[2] Radboud Univ Nijmegen, Med Ctr, Dept Rheumatol, NL-6525 ED Nijmegen, Netherlands
[3] Univ Edinburgh, Western Gen Hosp, Ctr Mol Med, Dept Rheumatol, Edinburgh, Midlothian, Scotland
[4] Univ Alicante, Rheumatol Sect, Dept Med, E-03080 Alicante, Spain
[5] Univ Miguel Hernandez, Gen Hosp, Alicante, Spain
[6] Hosp Univ Cruces, Div Rheumatol, Dept Rheumatol, Vizcaya, Spain
[7] Univ Padua, Dept Rheumatol, Rheumatol Unit, Padua, Italy
[8] Univ Lausanne Hosp, Dept Musculoskeletal Med, Lausanne, Switzerland
[9] Hop Lariboisiere, Ctr Viggo Petersen, Dept Rheumatol, F-75475 Paris, France
关键词
QUALITY-OF-LIFE; EVIDENCE BASED RECOMMENDATIONS; PRACTICE RESEARCH DATABASE; ASYMPTOMATIC HYPERURICEMIA; URIC-ACID; TASK-FORCE; MANAGEMENT; CARE; PREVALENCE; ADHERENCE;
D O I
10.1136/annrheumdis-2012-201687
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
Gout is the most common inflammatory arthritis and one in which pathogenesis and risk factors are best understood. One of the treatment objectives in current guidelines is 'cure'. However, audits show that only a minority of patients with gout receive adequate advice and treatment. Suboptimal care and outcomes reflect inappropriately negative perceptions of the disease, both in patients and providers. Historically, gout has been portrayed as a benign and even comical condition that is self-inflicted through overeating and alcohol excess. Doctors often focus on managing acute attacks rather than viewing gout as a chronic progressive crystal deposition disease. Urate-lowering treatment is underprescribed and often underdosed. Appropriate education of patients and doctors, catalysed by recent introduction of new urate-lowering treatments after many years with no drug development in the field, may help to overcome these barriers and improve management of this easily diagnosed and curable form of potentially severe arthritis.
引用
收藏
页码:1765 / 1770
页数:6
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