Diabetes, insulin secretion, and the pancreatic beta-cell mitochondrion.

被引：32

作者：

Langin, D ^{[1
]}

机构：

[1] INSERM, U317, F-31403 Toulouse, France

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2001年 / 345卷 / 24期

关键词：

D O I：

10.1056/NEJM200112133452412

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：1772 / 1774

页数：3

共 5 条

[1] Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production [J].

Arsenijevic, D ;

Onuma, H ;

Pecqueur, C ;

Raimbault, S ;

Manning, BS ;

Miroux, B ;

Couplan, E ;

Alves-Guerra, MC ;

Goubern, M ;

Surwit, R ;

Bouillaud, F ;

Richard, D ;

Collins, S ;

Ricquier, D .

NATURE GENETICS, 2000, 26 (04) :435-439

[2] Increased uncoupling protein-2 levels in β-cells are associated with impaired glucose-stimulated insulin secretion -: Mechanism of action [J].

Chan, CB ;

De Leo, D ;

Joseph, JW ;

McQuaid, TS ;

Ha, XF ;

Xu, F ;

Tsushima, RG ;

Pennefathner, PS ;

Salapatek, AMF ;

Wheeler, MB .

DIABETES, 2001, 50 (06) :1302-1310

[3] Uncoupling protein-2: A novel gene linked to obesity and hyperinsulinemia [J].

Fleury, C ;

Neverova, M ;

Collins, S ;

Raimbault, S ;

Champigny, O ;

LeviMeyrueis, C ;

Bouillaud, F ;

Seldin, MF ;

Surwit, RS ;

Ricquier, D ;

Warden, CH .

NATURE GENETICS, 1997, 15 (03) :269-272

[4] Uncoupling protein 2: A possible link between fatty acid excess and impaired glucose-induced insulin secretion? [J].

Lameloise, N ;

Muzzin, P ;

Prentki, M ;

Assimacopoulos-Jeannet, F .

DIABETES, 2001, 50 (04) :803-809

[5] Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, β cell dysfunction, and type 2 diabetes [J].

Zhang, CY ;

Baffy, G ;

Perret, P ;

Krauss, S ;

Peroni, O ;

Grujic, D ;

Hagen, T ;

Vidal-Puig, AJ ;

Boss, O ;

Kim, YB ;

Zheng, XX ;

Wheeler, MB ;

Shulman, GI ;

Chan, CB ;

Lowell, BB .

CELL, 2001, 105 (06) :745-755

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