Concise Review: Personalized Human Bone Grafts for Reconstructing Head and Face

被引:76
作者
Bhumiratana, Sarindr [1 ]
Vunjak-Novakovic, Gordana [1 ]
机构
[1] Columbia Univ, Dept Biomed Engn, New York, NY 10032 USA
关键词
Stem cell; Tissue regeneration; Bone; Bone marrow stromal cells; Cellular therapy; MESENCHYMAL STEM-CELLS; HUMAN MANDIBULAR CONDYLE; PLATELET-RICH PLASMA; HUMAN DENTAL-PULP; ENGINEERED BONE; CLINICAL-APPLICATIONS; CANCELLOUS BONE; ZYGOMATIC ARCH; SCAFFOLD; BIOLOGY;
D O I
10.5966/sctm.2011-0020
中图分类号
Q813 [细胞工程];
学科分类号
100113 [医学细胞生物学];
摘要
Regeneration of normal shape, architecture, and function of craniofacial tissues following congenital abnormality, trauma, or surgical treatment presents special problems to tissue engineering. Because of the great variations in properties of these tissues, currently available treatment options fall short of adequate care. We propose that the engineering of personalized bone graft customized to the patient and the specific clinical condition would revolutionize the way we currently treat craniofacial defects and discuss some of the current and emerging treatment modalities. STEM CELLS TRANSLATIONAL MEDICINE 2012;1:64-69
引用
收藏
页码:64 / 69
页数:6
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