CSF5-HIAA, suicide intent and hopelessness in the prediction of early suicide in male high-risk suicide attempters

被引:54
作者
Samuelsson, M [1 ]
Jokinen, J [1 ]
Nordström, A [1 ]
Nordström, P [1 ]
机构
[1] Karolinska Univ Hosp, Karolinska Psychiat Ctr, Psychiat Sect, Dept Clin Neurosci, SE-17176 Stockholm, Sweden
关键词
suicide; suicide attempt; CSF5-HIAA; serotonin; hopelessness; suicide intent;
D O I
10.1111/j.1600-0447.2005.00639.x
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objective: To study the predictive value of the Beck Suicide Intent Scale (SIS), the Beck Hopelessness Scale (BHS) and of 5-hydroxyindoleacetic acid (5-HIAA) in the cerebrospinal fluid for future early suicide in a group of high-risk male suicide attempters. Method: Fifteen consecutive male suicide attempters admitted to a psychiatric ward at the Karolinska Hospital, who were not receiving any treatment with antidepressants were diagnosed according to DSM-III, assessed with SIS and BHS and submitted to lumbar puncture. All patients were followed up for cause of death. Results: Five early suicides (within 2 years) were identified. Mean cerebrospinal fluid (CSF) 5-HIAA differed between suicides and survivors. Low CSF 5-HIAA was identified in those who committed early suicide. Neither the Suicide Intent Score nor the Hopelessness Score distinguished suicides from survivors. Conclusion: In high suicide risk hospitalized male psychiatric patients CSF 5-HIAA may be a better predictor of early suicide after attempted suicide than SIS or BHS.
引用
收藏
页码:44 / 47
页数:4
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