Sweet surrender to chemical genetics

被引：18

作者：

Tan, DS ^{[1
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Lab Chem & Chem Genet, New York, NY 10021 USA

来源：

NATURE BIOTECHNOLOGY | 2002年 / 20卷 / 06期

关键词：

D O I：

10.1038/nbt0602-561

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：561 / 563

页数：3

共 10 条

[1] Toward high-throughput synthesis of complex natural product-like compounds in the genomics and proteomics age [J].

Arya, P ;

Joseph, R ;

Chou, DTH .

CHEMISTRY & BIOLOGY, 2002, 9 (02) :145-156

[2] A one-bead, one-stock solution approach to chemical genetics:: part 1 [J].

Blackwell, HE ;

Pérez, L ;

Stavenger, RA ;

Tallarico, JA ;

Eatough, EC ;

Foley, MA ;

Schreiber, SL .

CHEMISTRY & BIOLOGY, 2001, 8 (12) :1167-1182

[3] Structure of the globular region of the prion protein Ure2 from the yeast Saccharomyces cerevisiae [J].

Bousset, L ;

Belrhali, H ;

Janin, J ;

Melki, R ;

Morera, S .

STRUCTURE, 2001, 9 (01) :39-46

[4] A one-bead, one-stock solution approach to chemical genetics: part 2 [J].

Clemons, PA ;

Koehler, AN ;

Wagner, BK ;

Sprigings, TG ;

Spring, DR ;

King, RW ;

Schreiber, SL ;

Foley, MA .

CHEMISTRY & BIOLOGY, 2001, 8 (12) :1183-1195

[5] Small-molecule microarrays: Covalent attachment and screening of alcohol-containing small molecules on glass slides [J].

Hergenrother, PJ ;

Depew, KM ;

Schreiber, SL .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2000, 122 (32) :7849-7850

[6] Dissecting glucose signalling with diversity-oriented synthesis and small-molecule microarrays [J].

Kuruvilla, FG ;

Shamji, AF ;

Sternson, SM ;

Hergenrother, PJ ;

Schreiber, SL .

NATURE, 2002, 416 (6881) :653-657

[7] Towards a pharmacological genetics [J].

Mitchison, Tim J. .

CHEMISTRY & BIOLOGY, 1994, 1 (01) :3-6

[8] Chemical genetics: Ligand-based discovery of gene function [J].

Stockwell, BR .

NATURE REVIEWS GENETICS, 2000, 1 (02) :116-125

[9] High-throughput screening of small molecules in miniaturized mammalian cell-based assays involving post-translational modifications [J].

Stockwell, BR ;

Haggarty, SJ ;

Schreiber, SL .

CHEMISTRY & BIOLOGY, 1999, 6 (02) :71-83

[10] The crystal structure of the nitrogen regulation fragment of the yeast prion protein Ure2p [J].

Umland, TC ;

Taylor, KL ;

Rhee, S ;

Wickner, RB ;

Davies, DR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (04) :1459-1464

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