Structure, development, and plasticity of dendritic spines

被引:406
作者
Harris, KM [1 ]
机构
[1] Childrens Hosp, Dept Neurol, Div Neurosci, Boston, MA 02115 USA
关键词
D O I
10.1016/S0959-4388(99)80050-6
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Dendritic spines are distinguished by their shapes, subcellular composition, and synaptic receptor subtypes. Recent studies show that actin-dependent movements take place in spine heads, that spines emerge from stubby and shaft synapses after dendritic filopodia disappear, and that spines can form without synaptic activation, are maintained by optimal activation, and are lost with excessive activation or during degeneration.
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页码:343 / 348
页数:6
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