Multifunctional nanostructured PLA materials for packaging and tissue engineering

被引:509
作者
Armentano, I. [1 ]
Bitinis, N. [2 ]
Fortunati, E. [1 ]
Mattioli, S. [1 ]
Rescignano, N. [1 ]
Verdejo, R. [2 ]
Lopez-Manchado, M. A. [2 ]
Kenny, J. M. [1 ,2 ]
机构
[1] Univ Perugia, Mat Engn Ctr, UdR INSTM, I-05100 Terni, Italy
[2] ICTP CSIC, Inst Ciencia & Tecnol Polimeros, Madrid 28006, Spain
关键词
PLA; Packaging; Tissue engineering; Nanoparticles; Bionanocomposites; Nanotopography; PLASTICIZED POLYLACTIDE/CLAY NANOCOMPOSITES; MESENCHYMAL STEM-CELLS; IN-VIVO DEGRADATION; POLY(LACTIC ACID); MECHANICAL-PROPERTIES; BARRIER PROPERTIES; LACTIC-ACID; LAYERED SILICATE; DRUG-DELIVERY; BIOMEDICAL APPLICATIONS;
D O I
10.1016/j.progpolymsci.2013.05.010
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
This review reports the promising prospects of poly(lactic acid) (PLA) based nanostructured materials considering two of their main potential uses, packaging and tissue engineering. The review initially discusses the significant progresses in the development of PLA bionanocomposites for packaging applications. The review then continues with a comprehensive analysis of the recent advances in tissue engineering applications focusing in the synthesis of PLA nanoparticles, the processing of PLA based multifunctional nanocomposites and PLA surface modification techniques. In summary, the review presents the current state of nanostructured PLA materials and establishes the exciting present and future prospects of these materials at the interface of chemistry, biology and material science. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1720 / 1747
页数:28
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