'Rab'ing up endosomal membrane transport

被引:22
作者
Deneka, M [1 ]
van der Sluijs, P
机构
[1] Univ Utrecht, Med Ctr, Dept Cell Biol, NL-3584 CX Utrecht, Netherlands
[2] Univ Utrecht, Med Ctr, Inst Biomembranes, NL-3584 CX Utrecht, Netherlands
关键词
D O I
10.1038/ncb0202-e33
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Early endosomes are the first sorting station from which endocytosed materials are targeted to various intracellular destinations. Recent work has identified the FYVE.-domain protein rabenosyn-5 as a bifunctional effector of the GTPases rab5 and rab4, physically connecting entry and recycling sites on early endosomes.
引用
收藏
页码:E33 / E35
页数:3
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