Repeated treatment protocols for melasma and acquired dermal melanocytosis

被引：27

作者：

Yoshimura, K ^{[1
]}

Sato, K ^{[1
]}

Aiba-Kojma, E ^{[1
]}

Matsumoto, D ^{[1
]}

Machino, C ^{[1
]}

Nagase, T ^{[1
]}

Gonda, K ^{[1
]}

Koshima, I ^{[1
]}

机构：

[1] Univ Tokyo, Sch Med, Dept Plast Surg, Bunkyo Ku, Tokyo 1138655, Japan

来源：

DERMATOLOGIC SURGERY | 2006年 / 32卷 / 03期

关键词：

D O I：

10.1111/j.1524-4725.2006.32074.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 [皮肤病与性病学];

摘要：

BACKGROUND AND OBJECTIVE Melasma and acquired dermal melanocytosis (ADM; acquired bilateral nevus of Ota-like macules) are both seen most commonly symmetrically on the face of women with darker skin and are also known as difficult conditions to treat. METHODS Our topical bleaching protocol with 0.1 to 0.4% tretinoin gel and 5% hydroquinone was performed repeatedly (1-3 times) for melasma (n=163), and a combination treatment with topical bleaching and Q-switched ruby (QSR) laser was performed repeatedly (1-3 times) for ADM (n = 62). RESULTS There is a significant correlation between clinical results (clearance of pigmentation) and the number of sessions in both melasma (p=.019) and ADM (p <.0001). CONCLUSION The repeated treatment protocol for melasma and ADM showed successful clinical results compared with conventional ones, and they may be applied to other pigment conditions. It may be better that epidermal and dermal pigmentations are treated separately, especially in dark-skinned people who are more likely to suffer postinflammatory hyperpigmentation after inflammation-inducing therapies.

引用

页码：365 / 371

页数：7

共 15 条

[1]

The combination of glycolic acid and hydroquinone or kojic acid for the treatment of melasma and related conditions [J].