Novel ways for immune intervention in immunotherapy: Mucosal allergy vaccines

被引：27

作者：

Mascarell, Laurent ^{[1
]}

Van Overtvelt, Laurence ^{[1
]}

Moingeon, Philippe ^{[1
]}

机构：

[1] Stallergenes SA, Res & Dev, F-92160 Antony, France

来源：

IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA | 2006年 / 26卷 / 02期

关键词：

D O I：

10.1016/j.iac.2006.02.009

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Allergen-specific immunotherapy is currently the only curative treatment for allergy Subcutaneous immunotherapy (SCIT) has been successfully used to treat patients who are allergic to insect venom, house dust mites, or tree or grass pollens. In the context of potentially severe, albeit infrequent, side effects associated with SCIT, mucosal routes of administration are being investigated to conduct allergenic desensitization. This article reviews recent developments in the field of nasal, oral, and sublingual immunotherapy as they relate to safety, clinical efficacy, and immune mechanisms of action.

引用

页码：283 / +

页数：26

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