The factor V Leiden mutation (R506Q) is not a major risk factor for migrainous cerebral infarction

被引：15

作者：

Haan, J

Kappelle, LJ

deRonde, H

Ferrari, MD

Bertina, RM

机构：

[1] UNIV LEIDEN HOSP, HEMOSTASIS & THROMBOSIS RES CTR, NL-2300 RC LEIDEN, NETHERLANDS

[2] UNIV UTRECHT HOSP, DEPT NEUROL, UTRECHT, NETHERLANDS

[3] RIJNLAND HOSP, DEPT NEUROL, LEIDERDORP, NETHERLANDS

来源：

CEPHALALGIA | 1997年 / 17卷 / 05期

关键词：

factor V mutation; migraine; migrainous cerebral infarction; resistance to activated protein C;

D O I：

10.1046/j.1468-2982.1997.1705605.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The etiology of migrainous cerebral infarction is unknown, but may involve prothrombotic coagulation abnormalities. Therefore, we studied resistance to activated protein C and the presence of the Arg506Gln factor V Leiden mutation in 20 patients with migrainous cerebral infarction. Only one heterozygous carrier of the mutation was found, whereas other patients did not carry the mutation. This indicates that the factor V Leiden mutation is not a major risk factor for migrainous cerebral infarction.

引用

页码：605 / 607

页数：3

共 28 条

[1] MUTATION IN BLOOD-COAGULATION FACTOR-V ASSOCIATED WITH RESISTANCE TO ACTIVATED PROTEIN-C [J].