Jusbetonin, the first indolo[3,2-b]quinoline alkaloid glycoside, from Justicia betonica

被引:79
作者
Subbaraju, GV [1 ]
Kavitha, J
Rajasekhar, D
Jimenez, JI
机构
[1] Sri Venkateswara Univ, Dept Chem, Tirupati 517502, Andhra Pradesh, India
[2] Univ Hawaii Manoa, Dept Chem, Honolulu, HI 96822 USA
来源
JOURNAL OF NATURAL PRODUCTS | 2004年 / 67卷 / 03期
关键词
D O I
10.1021/np030392y
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
A new indolo [3,2-b] quinoline alkaloid glycoside, jusbetonin (1), and three known alkaloids, namely, 10H-quindoline (2),6H-quinindoline (3), and 5H,6H-quinindolin-11-one (4), have been isolated from the leaves of Justicia betonica. The structure of I was established on the basis of 1D and 2D NMR (H-1-H-1 COSY, HMQC, and HMBC) and HRFABMS data. Compound 1 is the first example of a glycosylated indolo[3,2-b]quinoline alkaloid, while compound 4 was isolated for the first time from a natural source.
引用
收藏
页码:461 / 462
页数:2
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