An approach to oxazolidin-2-ones from the Baylis-Hillman adducts. Formal synthesis of a chloramphenicol derivative

被引：46

作者：

Coelho, F ^{[1
]}

Rossi, RC ^{[1
]}

机构：

[1] Univ Estadual Campinas, DQO, IQ, BR-13083970 Campinas, SP, Brazil

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 15期

关键词：

oxazolidin-2-one; Baylis-Hillman reaction; chloramphenicol derivative;

D O I：

10.1016/S0040-4039(02)00351-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In this communication we describe a straightforward and diastereoselective approach to prepare functionalised oxazolidin-2-ones from Baylis-Hillinan adducts. A stereoselective synthesis of a highly Substituted vicinal aminoalcohol and a formal synthesis of a chloramphenicol derivative are also described. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：2797 / 2800

页数：4

共 55 条

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