A highly enantioselective intramolecular Heck reaction with a monodentate ligand

被引：147

作者：

Imbos, R ^{[1
]}

Minnaard, AJ ^{[1
]}

Feringa, BL ^{[1
]}

机构：

[1] Univ Groningen, Dept Organ Chem, Stratingh Inst, NL-9747 AG Groningen, Netherlands

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2002年 / 124卷 / 02期

关键词：

D O I：

10.1021/ja017200a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient enantioselective intramolecular Heck reaction of cyclohexadienones, using readily available and modular TADDOL-based mono- and bidentate phosphoramidites as chiral ligands and not requiring any additives, has been developed. Excellent enantioselectivities up to 96% ee are reached for the first time in a Heck reaction with monodentate ligands. Copyright © 2002 American Chemical Society.

引用

页码：184 / 185

页数：2

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