Optimizing Trial Design Sequential, Adaptive, and Enrichment Strategies

被引：76

作者：

Mehta, Cyrus ^{[1
,6
]}

Gao, Ping ^{[5
]}

Bhatt, Deepak L. ^{[3
,4
]}

Harrington, Robert A. ^{[2
]}

Skerjanec, Simona ^{[5
]}

Ware, James H. ^{[6
]}

机构：

[1] Cytel Stat Software & Serv, Cambridge, MA 02139 USA

[2] Duke Clin Res Inst, Durham, NC USA

[3] Brigham & Womens Hosp, Boston, MA 02115 USA

[4] Vet Affairs Boston Healthcare Syst, Boston, MA USA

[5] Med Co, Parsippany, NJ USA

[6] Harvard Univ, Sch Publ Hlth, Boston, MA 02115 USA

来源：

CIRCULATION | 2009年 / 119卷 / 04期

关键词：

CLINICAL-TRIALS;

D O I：

10.1161/CIRCULATIONAHA.108.809707

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：597 / U199

页数：18

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