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TEM-24 produced by four different species of Enterobacteriaceae, including Providencia rettgeri, in a single patient

被引：45
作者：
Marchandin, H
Carriere, C
Sirot, D
Jean-Pierre, H
Darbas, H
机构：
[1] Hop Arnaud Villeneuve, Bacteriol Lab, Serv Bacteriol, F-34295 Montpellier 5, France
[2] Fac Med & Pharm, Serv Bacteriol, F-63001 Clermont Ferrand, France
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1999年 / 43卷 / 08期
关键词：
D O I：
10.1128/AAC.43.8.2069
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Four species of members of the family Enterobacteriaceae harboring extended-spectrum beta-lactamase (ESBL) were recovered in a single patient hospitalized in an intensive care unit. Among these isolates, we describe for the first time an ESBL-producing Providencia rettgeri strain. Bacteria from the same species were shown to be genetically related by pulsed-field gel electrophoresis analysis. These strains produced the same TEM derivative ESBL, characterized as TEM-24. This enzyme had the peculiarity of being encoded by a large conjugative plasmid of 180 kb, never previously described for such an ESBL.
引用
收藏
页码：2069 / 2073
页数：5
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