Normalization of nomenclature for peptide motifs as ligands of modular protein domains

被引:118
作者
Aasland, R [1 ]
Abrams, C
Ampe, C
Ball, LJ
Bedford, MT
Cesareni, G
Gimona, M
Hurley, JH
Jarchau, T
Lehto, VP
Lemmon, MA
Linding, R
Mayer, BJ
Nagai, M
Sudol, M
Walter, U
Winder, SJ
机构
[1] Univ Bergen, Dept Biol Mol, N-5020 Bergen, Norway
[2] Univ Penn, Div Hematol & Oncol, Philadelphia, PA 19014 USA
[3] State Univ Ghent, Dept Biochem, B-9000 Ghent, Belgium
[4] FMP, Res Inst Mol Pharmacol, Dept NMR & Struct Biol, FMP, D-13125 Berlin, Germany
[5] Univ Texas, Dept Carcinogenesis, Smithville, TX 78957 USA
[6] Univ Roma Tor Vergata, Dept Biol, I-00133 Rome, Italy
[7] Austrian Acad Sci, Dept Cell Biol, A-5020 Salzburg, Austria
[8] NIDDKD, Mol Biol Lab, NIH, Bethesda, MD 20892 USA
[9] Inst Klin Biochem & Pathobiochem, D-97078 Wurzburg, Germany
[10] Oulu Univ, Dept Pathol, Oulu, Finland
[11] Univ Penn, Sch Med, Dept Biochem & Biophys, Philadelphia, PA 19104 USA
[12] European Mol Biol Lab, Biocomp Unit, D-69117 Heidelberg, Germany
[13] Univ Connecticut, Dept Genet & Dev Biol, Farmington, CT 06030 USA
[14] Mt Sinai Med Ctr, Dept Med, New York, NY 10029 USA
[15] Univ Glasgow, Div Biochem & Mol Biol, Glasgow G12 8QQ, Lanark, Scotland
关键词
protein-protein interaction; peptide motif; protein domain; specificity and recognition; proteomics; glossary; nomenclature; ASCII format;
D O I
10.1016/S0014-5793(01)03295-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 [生物化学与分子生物学]; 081704 [应用化学];
摘要
We propose a normalization of symbols and terms used to describe, accurately and succinctly, the detailed interactions between amino acid residues of pairs of interacting proteins at protein:protein (or protein: peptide) interfaces. Our aim is to unify several diverse descriptions currently in use in order to facilitate communication in the rapidly progressing field of signaling by protein domains. In order for the nomenclature to be convenient and widely used, we also suggest a parallel set of symbols restricted to the ASCII format allowing accurate parsing of the nomenclature to a computer-readable form. This proposal will be reviewed in the future and will therefore be open for the inclusion of new rules, modifications and changes. (C) 2002 Federation of European Biochemical Societies. Published by Elsevier Science B.V. All rights reserved.
引用
收藏
页码:141 / 144
页数:4
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