Improved syntheses of halofuranose derivatives with the desired alpha-configuration

被引：4

作者：

Chin, TM ^{[1
]}

Huang, LK ^{[1
]}

Kan, LS ^{[1
]}

机构：

[1] ACAD SINICA,INST CHEM,TAIPEI 11529,TAIWAN

来源：

JOURNAL OF THE CHINESE CHEMICAL SOCIETY | 1997年 / 44卷 / 04期

关键词：

1-chloro-(2-deoxy-)alpha-D-ribofuranose derivative; chlorination; stereo-control; alpha-configuration;

D O I：

10.1002/jccs.199700062

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Chlorination of ribofuranose or 2-deoxyribofuranose derivatives was carried out in a 1,4-dioxane solution of hydrogen chloride. This improved procedure allowed the syntheses of 1-chloro-alpha-D-ribofuranose and 1-chloro-2-deoxy-Phi-D-ribofuranose derivatives and offered ease of handling, high yield, and the stereocontrolled alpha-configuration at C-1.

引用

收藏

页码：413 / 416

页数：4

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