Chimerism and transplantation tolerance: Cause and effect

被引:157
作者
Wood, K [1 ]
Sachs, DH [1 ]
机构
[1] HARVARD UNIV,MASSACHUSETTS GEN HOSP,SCH MED,TRANSPLANTAT BIOL RES CTR,BOSTON,MA 02129
来源
IMMUNOLOGY TODAY | 1996年 / 17卷 / 12期
关键词
D O I
10.1016/S0167-5699(96)10069-4
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Evidence for persistence of donor leukocytes in recipients of long-term organ allografts has prompted the hypothesis that such microchimerism is not only essential to graft survival but that donor and host cells both play active roles. Here, Kathryn Wood and David Sachs caution that the jury is still out on whether such microchimerism is the cause or merely the consequence of long-term allografting.
引用
收藏
页码:584 / 587
页数:4
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