7-amino-4-methyl-6-sulfocoumarin-3-acetic acid: A novel blue fluorescent dye for protein labeling

被引：4

作者：

Leung, WY

Trobridge, PA

Haugland, RP

Mao, F

机构：

[1] Mol Probes Inc, Eugene, OR 97402 USA

[2] Univ Washington, Dept Immunol, Seattle, WA 98195 USA

[3] Therasense Inc, Alameda, CA 94502 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1999年 / 9卷 / 15期

关键词：

D O I：

10.1016/S0960-894X(99)00364-9

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

7-Amino-4-methyl-6-sulfocoumarin-3-acetic acid (AMCA-S, also called Alexa(TM) 350) 2 was synthesized as a new water-soluble blue fluorescent dye for protein labeling. Compared with its nonsulfonated counterpart (AMCA) 1 the new dye gave significantly higher fluorescence quantum yields on proteins. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：2229 / 2232

页数：4

共 17 条

[1] REDUCED BOVINE PANCREATIC TRYPSIN-INHIBITOR HAS A COMPACT STRUCTURE [J].