Cardiovascular risk reduction in diabetes: underemphasised and overdue. Messages from major trials

被引：14

作者：

Adler, AI ^{[1
]}

机构：

[1] Univ Oxford, Radcliffe Infirm, Diabet Trials Unit, Oxford OX2 6HE, England

来源：

CLINICAL MEDICINE | 2001年 / 1卷 / 06期

关键词：

D O I：

10.7861/clinmedicine.1-6-472

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Diabetes markedly increases the risk of coronary artery disease and death, but is underrecognised as a cardiovascular risk factor, despite the existence of effective treatments. Because patients with diabetes are at high risk for coronary disease, they have more to gain from prevention. There is evidence from clinical trials that select cardiovascular therapies may work better in diabetes, beyond their expected benefit, and may prevent diabetes itself.

引用

页码：472 / 477

页数：6

共 50 条

[1]

Adler A, 1998, DIABETES, V47, pA71

[2] Association of systolic blood pressure with macrovascular and microvascular complications of type 2 diabetes (UKPDS 36): prospective observational study [J].

Adler, AI ;

Stratton, IM ;

Neil, HAW ;

Yudkin, JS ;

Matthews, DR ;

Cull, CA ;

Wright, AD ;

Turner, RC ;

Holman, RR .

BMJ-BRITISH MEDICAL JOURNAL, 2000, 321 (7258) :412-419

[3] Effective postponement of diabetic nephropathy with enalapril in normotensive type 2 diabetic patients with microalbuminuria [J].

Ahmad, J ;

Siddiqui, MA ;

Ahmad, H .

DIABETES CARE, 1997, 20 (10) :1576-1581

[4]

Alderman EL, 2000, J AM COLL CARDIOL, V35, P1122

[5]

Altman D.G., 1991, PRACTICAL STAT MED R, V1st, P403, DOI [10.1002/sim.4780101015, DOI 10.1002/SIM.4780101015]

[6]

*AM DIAB ASS, 2001, DIABETES CARE S1, V24, pS33

[7] Need for large scale randomised evidence about lowering LDL cholesterol in people with diabetes mellitus: MRC/BHF heart protection study and other major trials [J].

Armitage, J ;

Collins, R .

HEART, 2000, 84 (04) :357-360

[8] Pioglitazone hydrochloride monotherapy improves glycemic control in the treatment of patients with type 2 diabetes - A 6-month randomized placebo-controlled dose-response study [J].

Aronoff, S ;

Rosenblatt, S ;

Braithwaite, S ;

Egan, JW ;

Mathisen, AL ;

Schneider, RL .

DIABETES CARE, 2000, 23 (11) :1605-1611

[9] High blood glucose concentration is a risk factor for mortality in middle-aged nondiabetic men -: 20-year follow-up in the Whitehall Study, the Paris Prospective Study, and the Helsinki Policemen Study [J].

Balkau, B ;

Shipley, M ;

Jarrett, RJ ;

Pyörälä, K ;

Pyörälä, M ;

Forhan, A ;

Eschwège, E .

DIABETES CARE, 1998, 21 (03) :360-367

[10] Glucose tolerance and cardiovascular mortality -: Comparison of fasting and 2-hour diagnostic criteria [J].

Borch-Johnsen, K ;

Neil, A ;

Balkau, B ;

Larsen, S ;

Nissinen, A ;

Pekkanen, J ;

Tuomilehto, J ;

Jousilahti, P ;

Lindstrom, J ;

Pyörälä, M ;

Pyörälä, K ;

Eschwege, E ;

Gallus, G ;

Garancini, MP ;

Bouter, LM ;

Dekker, JM ;

Heine, RJ ;

Nijpels, HG ;

Stehouwer, CDA ;

Feskens, EJM ;

Kromhout, D ;

Peltonen, M ;

Pajak, A ;

Eriksson, J ;

Qiao, Q .

ARCHIVES OF INTERNAL MEDICINE, 2001, 161 (03) :397-405

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