Pan-dengue virus detection by PCR for travelers returning from the tropics

被引:14
作者
Dumoulin, Alexis
Marti, Hanspeter [2 ]
Panning, Marcus [3 ]
Hatz, Christoph [4 ]
Hirsch, Hans H. [1 ,5 ]
机构
[1] Univ Basel, Zentrum Infekt Diagnost, Inst Med Microbiol, Dept Biomed,Div Diagnost, CH-4003 Basel, Switzerland
[2] Swiss Trop Inst, Dept Diagnost, CH-4002 Basel, Switzerland
[3] Bernhard Nocht Inst Trop Med, Hamburg, Germany
[4] Swiss Trop Inst, Dept Med, CH-4002 Basel, Switzerland
[5] Univ Basel Hosp, Infect Dis & Hosp Epidemiol, CH-4031 Basel, Switzerland
关键词
D O I
10.1128/JCM.01294-08
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We performed dengue virus (DENV) serology and quantitative real-time pan-DENV reverse transcription-PCR (RT-PCR) on 186 sera of 171 patients returning from the tropics. DENV loads significantly decreased with increasing times of disease and were higher in immunoglobulin M-negative samples. In the first week of disease, pan-DENV RT-PCR is the test of choice.
引用
收藏
页码:3104 / 3106
页数:3
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