Sorption of the antimicrobial ciprofloxacin to aluminum and iron hydrous oxides

被引:364
作者
Gu, C [1 ]
Karthikeyan, KG [1 ]
机构
[1] Univ Wisconsin, Dept Biol Syst Engn, Environm Chem & Technol Program, Madison, WI 53706 USA
关键词
D O I
10.1021/es051109f
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Solution chemistry (pH, ionic strength (l), and sorbate-to-sorbent ratio) effects on ciprofloxacin sorption to hydrous oxides of Al (HAO) and Fe (HFO) were investigated using macroscopic and spectroscopic analyses. Sorption to both HAO and HFO showed a strong pH-dependent behavior, following the fraction of zwitterionic species over the entire pH range studied. Increase in /from 0.01 to 0.5 M had an insignificant effect on the extent of ciprofloxacin sorption, and isotherms were well-described by the Langmuir model. HFO possessed a higher sorption capacity (0.066 mmol kg(-1)) than HAO (0.041 mmol kg(-1)). Ligand-promoted dissolution of hydrous oxides, more pronounced for HAO, was observed in the presence of ciprofloxacin, but at a fairly high initial concentration (0.5 mM). Attenuated total reflectance Fourier transform infrared spectroscopy analysis indicated that different types of ciprofloxacin surface complexes are formed with HAO and HFO; while a monodentate mononuclear complex (with -COO-) appears likely between ciprofloxacin and HAO, keto 0 and one 0 from COO- seem to be involved in the formation of a six-membered ring with Fe on the HFO surface. The study results are expected to increase our understanding of the environmental reactivity of fluoroquinolones, an important class of antimicrobial compounds.
引用
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页码:9166 / 9173
页数:8
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