MAP kinase cascades: Scaffolding signal specificity

被引：41

作者：

van Drogen, F ^{[1
]}

Peter, M ^{[1
]}

机构：

[1] Swiss Inst Expt Canc Res, ISREC, CH-1066 Epalinges, VD, Switzerland

来源：

CURRENT BIOLOGY | 2002年 / 12卷 / 02期

关键词：

D O I：

10.1016/S0960-9822(01)00672-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Scaffold proteins organize many MAP kinase pathways by interacting with several components of these cascades. Recent studies suggest that scaffold proteins provide local activation platforms that contribute to signal specificity by insulating different MAP kinase pathways.

引用

页码：R53 / R55

页数：3

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