Dopaminergic hypersensitivity in patients with Parkinson disease and migraine

被引:13
作者
Cubo, E
Kompoliti, K
Leurgans, SE
Raman, R
机构
[1] Clin Zarzuela, Dept Neurol, Madrid, Spain
[2] Rush Presbyterian St Lukes Med Ctr, Biostat Sect, Dept Prevent Med, Chicago, IL 60612 USA
[3] Rush Presbyterian St Lukes Med Ctr, Sect Movement Disorders, Dept Neurol Sci, Chicago, IL 60612 USA
关键词
Parkinson disease; migraine; headache;
D O I
10.1097/00002826-200401000-00009
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Because migraine has been associated with dopaminergic receptor hypersensitivity, the authors hypothesized that patients with Parkinson disease with current or prior migraine have better dopaminergic response and less motor disability than Parkinson disease patients without migraine. Twenty-eight patients with Parkinson disease were included and matched (10 patients with migraine and 18 patients without migraine). Patients with Parkinson disease and migraine showed greater motor improvement during the ON state than patients without migraine with the same medication exposure. These data support the hypothesis that migraine may be associated with dopaminergic hypersensitivity.
引用
收藏
页码:30 / 32
页数:3
相关论文
共 13 条
[1]   Dopamine and migraine: does Parkinson's disease modify migraine course? [J].
Barbanti, P ;
Fabbrini, G ;
Vanacore, N ;
Rum, A ;
Lenzi, G ;
Meco, G ;
Cerbo, R .
CEPHALALGIA, 2000, 20 (08) :720-723
[2]   APOMORPHINE-INDUCED YAWNING IN MIGRAINE PATIENTS - ENHANCED RESPONSIVENESS [J].
BLIN, O ;
AZULAY, JP ;
MASSON, G ;
AUBRESPY, G ;
SERRATRICE, G .
CLINICAL NEUROPHARMACOLOGY, 1991, 14 (01) :91-95
[3]  
Bodenmann P, 2001, REV NEUROL-FRANCE, V157, P45
[4]  
DELZOMPO M, 1995, HEADACHE, V35, P222
[5]  
Fahn S., RECENT DEV PARKINSON, V2, P153, DOI DOI 10.1002/ANA.410220556
[6]   PARKINSONISM - ONSET PROGRESSION AND MORTALITY [J].
HOEHN, MM ;
YAHR, MD .
NEUROLOGY, 1967, 17 (05) :427-&
[7]   RANDOMIZED DOUBLE-BLIND TRIAL OF INTRAVENOUS PROCHLORPERAZINE FOR THE TREATMENT OF ACUTE HEADACHE [J].
JONES, J ;
SKLAR, D ;
DOUGHERTY, J ;
WHITE, W .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1989, 261 (08) :1174-1176
[8]   Posteroventral medial pallidotomy in advanced Parkinson's disease [J].
Lang, AE ;
Lozano, AM ;
Montgomery, E ;
Duff, J ;
Tasker, R ;
Hutchinson, W .
NEW ENGLAND JOURNAL OF MEDICINE, 1997, 337 (15) :1036-1042
[9]   The prevalence and characteristics of migraine in a population-based cohort - The GEM Study [J].
Launer, LJ ;
Terwindt, GM ;
Ferrari, MD .
NEUROLOGY, 1999, 53 (03) :537-542
[10]   A SURVEY OF HEADACHE IN PARKINSONS-DISEASE [J].
LORENTZ, IT .
CEPHALALGIA, 1989, 9 (02) :83-86