Allylation of imines with allyltrimethylsilane and experimental evidences for a fluoride-triggered autocatalysis mechanism of the Sakurai-Hosomi reaction

被引：78

作者：

Wang, DK ^{[1
]}

Zhou, YG ^{[1
]}

Tang, Y ^{[1
]}

Hou, XL ^{[1
]}

Dai, LX ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Organomet Chem Lab, Shanghai 200032, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1999年 / 64卷 / 12期

关键词：

D O I：

10.1021/jo980767y

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This article reports the reaction of allyltrimethylsilane 1 with aldimines 2 in the presence of tetra-n-butylammonium fluoride to give the corresponding homoallylamines 3 in moderate to excellent yields. The allylation mechanism of imines as well as that of aldehydes can be reasonably interpreted by a fluoride-triggered autocatalytic procedure.

引用

页码：4233 / 4237

页数：5

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