Focus on molecules: Optineurin

被引：14

作者：

Chalasani, Madhavi Latha ^{[1
]}

Balasubranianian, Dorairajan ^{[1
]}

Swarup, Ghanshyam ^{[2
]}

机构：

[1] LV Prasad Eye Inst, Hyderabad 500034, Andhra Pradesh, India

[2] Ctr Cellular & Mol Biol, Hyderabad 500007, Andhra Pradesh, India

来源：

EXPERIMENTAL EYE RESEARCH | 2008年 / 87卷 / 01期

关键词：

optineurin; glaucoma; retinal ganglion cells; mutation; cell death; tumor necrosis factor; NF-kappa B;

D O I：

10.1016/j.exer.2007.10.021

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

引用

页码：1 / 2

页数：2

共 4 条

[1] A glaucoma-associated mutant of optineurin selectively induces death of retinal ganglion cells which is inhibited by antioxidants [J].

Chalasani, Madhavi Latha ;

Radha, Vegesna ;

Gupta, Vijay ;

Agarwal, Neeraj ;

Balasubramanian, Dorairajan ;

Swarup, Ghanshyam .

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2007, 48 (04) :1607-1614

[2] Adult-onset primary open-angle glaucoma caused by mutations in optineurin [J].

Rezaie, T ;

Child, A ;

Hitchings, R ;

Brice, G ;

Miller, L ;

Coca-Prados, M ;

Héon, E ;

Krupin, T ;

Ritch, R ;

Kreutzer, D ;

Crick, RP ;

Sarfarazi, M .

SCIENCE, 2002, 295 (5557) :1077-1079

[3] Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis [J].

Sahlender, DA ;

Roberts, RC ;

Arden, SD ;

Spudich, G ;

Taylor, MJ ;

Luzio, JP ;

Kendrick-Jones, J ;

Buss, F .

JOURNAL OF CELL BIOLOGY, 2005, 169 (02) :285-295

[4] Optineurin negatively regulates TNFα-induced NF-κB activation by competing with NEMO for ubiquitinated RIP [J].

Zhu, Guozhi ;

Wu, Chuan-Jin ;

Zhao, Yongge ;

Ashwell, Jonathan D. .

CURRENT BIOLOGY, 2007, 17 (16) :1438-1443

← 1 →