Conditional Expression of Genes in the Respiratory Epithelium in Transgenic Mice Cautionary Notes and Toward Building a Better Mouse Trap

被引：71

作者：

Perl, Anne-Karina ^{[1
]}

Zhang, Liqian

Whitsett, Jeffrey A.

机构：

[1] Childrens Hosp, Med Ctr, Cincinnati, OH 45229 USA

来源：

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY | 2009年 / 40卷 / 01期

关键词：

LUNG; INFLAMMATION; EMPHYSEMA; ELEMENTS;

D O I：

10.1165/rcmb.2008-0011ED

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1 / 3

页数：3

共 12 条

[1] Temporal and spatial regulation of VEGF-A controls vascular patterning in the embryonic lung [J].

Akeson, AL ;

Greenberg, JM ;

Cameron, JE ;

Thompson, FY ;

Brooks, SK ;

Wiginton, D ;

Whitsett, JA .

DEVELOPMENTAL BIOLOGY, 2003, 264 (02) :443-455

[2] Reversibility of lung inflammation caused by SP-B deficiency [J].

Ikegami, M ;

Whitsett, JA ;

Martis, PC ;

Weaver, TE .

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2005, 289 (06) :L962-L970

[3] GP130-STAT3 regulates epithelial cell migration and is required for repair of the bronchiolar epithelium [J].

Kida, Hiroshi ;

Mucenski, Michael L. ;

Thitoff, Angela R. ;

Le Cras, Timothy D. ;

Park, Kwon-Sik ;

Ikegami, Machiko ;

Mueller, Werner ;

Whitsett, Jeffrey A. .

AMERICAN JOURNAL OF PATHOLOGY, 2008, 172 (06) :1542-1554

[4] Interleukin-1β causes pulmonary inflammation, emphysema, and airway remodeling in the adult murine lung [J].

Lappalainen, U ;

Whitsett, JA ;

Wert, SE ;

Tichelaar, JW ;

Bry, K .

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2005, 32 (04) :311-318

[5] Conditional gene expression in the respiratory epithelium of the mouse [J].

Perl, AKT ;

Tichelaar, JW ;

Whitsett, JA .

TRANSGENIC RESEARCH, 2002, 11 (01) :21-29

[6] Early restriction of peripheral and proximal cell lineages during formation of the lung [J].

Perl, AKT ;

Wert, SE ;

Nagy, A ;

Lobe, CG ;

Whitsett, JA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (16) :10482-10487

[7] Conditional recombination reveals distinct subsets of epithelial cells in trachea, bronchi, and alveoli [J].

Perl, AKT ;

Wert, SE ;

Loudy, DE ;

Shan, Z ;

Blair, PA ;

Whitsett, JA .

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2005, 33 (05) :455-462

[8] Expression of the reverse tetracycline-transactivator gene causes emphysema-like changes in mice [J].

Sisson, TH ;

Hansen, JM ;

Shah, M ;

Hanson, KE ;

Du, M ;

Ling, T ;

Simon, RH ;

Christensen, PJ .

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2006, 34 (05) :552-560

[9]

STRIPP BR, 1992, J BIOL CHEM, V267, P14703

[10] Conditional expression of fibroblast growth factor-7 in the developing and mature lung [J].

Tichelaar, JW ;

Lu, W ;

Whitsett, JK .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (16) :11858-11864

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