Bacterial cell-to-cell communication: Sorry, can't talk now - gone to lunch!

被引：243

作者：

Winzer, K

Hardie, KR

Williams, P ^{[1
]}

机构：

[1] Univ Nottingham, Queens Med Ctr, Inst Infect & Immun, Nottingham NG7 2UH, England

[2] Univ Nottingham, Sch Pharmaceut Sci, Nottingham NG7 2RD, England

来源：

CURRENT OPINION IN MICROBIOLOGY | 2002年 / 5卷 / 02期

关键词：

D O I：

10.1016/S1369-5274(02)00304-1

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The identification of novel bacterial cell-to-cell communication (quorum sensing) systems based on diffusible signal molecules, such as indole and the LuxS autoinducer-2, requires discrimination between true signalling molecules and metabolites present in culture supernatants. This depends on rigorous chemical characterisation and demonstration that the molecule controls cellular responses beyond those required to metabolise or detoxify the signal.

引用

收藏

页码：216 / 222

页数：7

相关论文

共 46 条

[1]

BACADELANCEY RR, 1999, P NATL ACAD SCI USA, V97, P3526

[2] How bacteria talk to each other: regulation of gene expression by quorum sensing [J].

Bassler, BL .

CURRENT OPINION IN MICROBIOLOGY, 1999, 2 (06) :582-587

[3] MULTIPLE SIGNALING SYSTEMS CONTROLLING EXPRESSION OF LUMINESCENCE IN VIBRIO-HARVEYI - SEQUENCE AND FUNCTION OF GENES ENCODING A 2ND SENSORY PATHWAY [J].

BASSLER, BL ;

WRIGHT, M ;

SILVERMAN, MR .

MOLECULAR MICROBIOLOGY, 1994, 13 (02) :273-286

[4] Cross-species induction of luminescence in the quorum-sensing bacterium Vibrio harveyi [J].

Bassler, BL ;

Greenberg, EP ;

Stevens, AM .

JOURNAL OF BACTERIOLOGY, 1997, 179 (12) :4043-4045

[5] LuxS-dependent quorum sensing in Porphyromonas gingivalis modulates protease and haemagglutinin activities but is not essential for virulence [J].

Burgess, NA ;

Kirke, DF ;

Williams, P ;

Winzer, K ;

Hardie, KR ;

Meyers, NL ;

Aduse-Opoku, J ;

Curtis, MA ;

Cámara, M .

MICROBIOLOGY-SGM, 2002, 148 :763-772

[6] Structural identification of a bacterial quorum-sensing signal containing boron [J].

Chen, X ;

Schauder, S ;

Potier, N ;

Van Dorsselaer, A ;

Pelczer, I ;

Bassler, BL ;

Hughson, FM .

NATURE, 2002, 415 (6871) :545-549

[7] Signaling system in Porphyromonas gingivalis based on a LuxS protein [J].

Chung, WSO ;

Park, Y ;

Lamont, RJ ;

McNab, R ;

Barbieri, B ;

Demuth, DR .

JOURNAL OF BACTERIOLOGY, 2001, 183 (13) :3903-3909

[8] Availability of glutamate and arginine during acid challenge determines cell density-dependent survival phenotype of Escherichia coli strains [J].

Cui, SH ;

Meng, JH ;

Bhagwat, AA .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2001, 67 (10) :4914-4918

[9]

Datta AR, 1999, FEMS MICROBIOL LETT, V181, P289, DOI 10.1016/S0378-1097(99)00532-7

[10] Shigella flexneri LuxS quorum-sensing system modulates virB expression but is not essential for virulence [J].

Day, WA ;

Maurelli, AT .

INFECTION AND IMMUNITY, 2001, 69 (01) :15-23

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