A Multicenter Study on Central Venous Catheter-Associated Infections in Italy

被引：21

作者：

Donelli, G. ^{[1
]}

De Paoli, P. ^{[2
]}

Fadda, G. ^{[3
]}

Marone, P. ^{[4
]}

Nicoletti, G. ^{[5
]}

Varaldo, P. E. ^{[6
]}

机构：

[1] Ist Super Sanita, Lab Ultrastrutture, I-00161 Rome, Italy

[2] IRCCS Ctr Riferimento Oncol, Lab Microbiol, Aviano, Italy

[3] Univ Cattolica Sacro Cuore, Ist Microbiol, Rome, Italy

[4] IRCCS Policlin S Matteo, Lab Batteriol & Microbiol, Pavia, Italy

[5] Univ Catania, Dipartimento Sci Microbiol & Sci Ginecol, I-95124 Catania, Italy

[6] Univ Ancona, Ist Microbiol, I-60128 Ancona, Italy

来源：

JOURNAL OF CHEMOTHERAPY | 2001年 / 13卷

关键词：

Central venous catheters; microbial colonization; bloodstream infections; antibiotic-resistance; biofilms; catheter quality; scanning electron microscopy;

D O I：

10.1179/joc.2001.13.Supplement-2.251

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In a 1-year multicenter study the microbial colonization of 1154 central venous catheters (CVCs) was investigated. Catheters explanted either from immunocompromised or immunocompetent patients were collected and analyzed by five clinical microbiology laboratories located in Ancona, Aviano, Catania, Pavia and Rome, Italy. A further aim was to investigate, by scanning electron microscopy, the features of currently used catheters, both new and explanted from patients, analyzing their surface quality, the influence of the host protein biofilm on their microbial colonization, the modifications caused by their permanence in the body and the relationship between these factors and the occurrence of infections.

引用

页码：251 / 262

页数：12

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