A synthesis of ynolates via the cleavage of ester dianions

被引：39

作者：

Shindo, M

机构：

[1] Institute for Medicinal Resources, University of Tokushima, Sho-machi 1

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 25期

关键词：

D O I：

10.1016/S0040-4039(97)00924-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new method for ynolate synthesis via the cleavage of ester dianions has been developed. The key intermediates, ester dianions, generated from alpha-bromocarboxylic acid ester enolates via lithium-halogen exchange turned out to be so labile that they were cleaved rapidly to give ynolates. (C) 1997 Elsevier Science Ltd.

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页码：4433 / 4436

页数：4

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