Simultaneous determination of heavy metal pollution in commercial traditional Chinese medicines in China

被引:20
作者
Liu, Yougang [1 ,2 ]
Wu, Jianwei [1 ,3 ]
Wei, Wang [2 ]
Xu, Rong [1 ]
机构
[1] Chinese Acad Med Sci, Peking Union Med Coll, Inst Med Plant Dev, Beijing 100193, Peoples R China
[2] Tianjin Univ Tradit Chinese Med, Tianjin 300193, Peoples R China
[3] China Natl Grp Corp Tradit & Herbal Med, Technol Dev Ctr, Beijing 102600, Peoples R China
关键词
Heavy metal; Atomic absorption spectrophotometry; Traditional Chinese medicines; Pollution; ATOMIC-ABSORPTION-SPECTROMETRY; ANODIC-STRIPPING VOLTAMMETRY; FLOW-INJECTION; SAMPLES; PLANTS; DRUGS; ZN; CD; PB; SE;
D O I
10.1007/s11418-012-0656-9
中图分类号
R914 [药物化学];
学科分类号
100705 [微生物与生化药学];
摘要
A rapid and accurate method of quantifying heavy metal pollution in commercial traditional Chinese medicines (TCMs) is described. The method uses modified wet digestion for sample preparation and atomic absorption spectrophotometry for detecting the content of copper (Cu), cadmium (Cd), arsenic (As), lead (Pb) and mercury (Hg). The determination limits of the method were 0.001, 0.002, 0.001, 0.001 and 0.001 mg/kg for Cu, Cd, As, Pb and Hg, respectively. The method was applied to the quantification of heavy metal pollution in 50 different commercial TCMs in a total of 250 samples. Heavy metal contents in the samples investigated were found at different levels. The level of As did not exceed the legal limit stated in the China pharmacopoeia 2010, whereas Cu, Cd, Pb and Hg were above permitted levels in some samples.
引用
收藏
页码:887 / 893
页数:7
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