Impairment of mobility in endodermal cells by FAK deficiency

被引：58

作者：

Ilic, D

Kanazawa, S

Furuta, Y

Yamamoto, T

Aizawa, S

机构：

[1] KUMAMOTO UNIV,SCH MED,DEPT MORPHOGENESIS,INST MOLEC EMBRYOL & GENET,KUMAMOTO 860,JAPAN

[2] UNIV TOKYO,INST MED SCI,DEPT ONCOL,MINATO KU,TOKYO 108,JAPAN

来源：

EXPERIMENTAL CELL RESEARCH | 1996年 / 222卷 / 02期

关键词：

D O I：

10.1006/excr.1996.0038

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Focal adhesion kinase (FAK) is a novel nonreceptor protein tyrosine kinase that localizes in focal adhesions. It is expressed in a variety of cell types, and we reported earlier that its deficiency causes a decrease of mobility in mesodermal cells with enhanced formation of focal adhesions. With embryoid bodies generated from embryonic stem cells, we also observed a decrease of mobility in FAK-deficient endodermal cells with enhanced focal adhesion formation. (C) 1996 Academic Press, Inc.

引用

页码：298 / 303

页数：6

共 28 条

[1] LOCALIZATION AND SYNTHESIS OF SOME COLLAGEN TYPES IN DEVELOPING MOUSE EMBRYOS [J].