Oligomeric acylphloroglucinols from myrtle (Myrtus communis)

被引：85

作者：

Appendino, G

Bianchi, F

Minassi, A

Sterner, O

Ballero, M

Gibbons, S

机构：

[1] Univ Piemonte Orientale, DISCAFF, I-28100 Novara, Italy

[2] Lund Univ, Dept Organ & Bioorgan Chem, S-22100 Lund, Sweden

[3] Univ Cagliari, Dipartimento Sci Bot, I-09123 Cagliari, Italy

[4] Univ London, Sch Pharm, Ctr Pharmacognosy & Phytotherapy, London WC1N 1AX, England

来源：

JOURNAL OF NATURAL PRODUCTS | 2002年 / 65卷 / 03期

关键词：

D O I：

10.1021/np010441b

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The dimeric nonprenylated acylphloroglucinol semimyrtucommulone (6) was obtained from the leaves of. myrtle (Myrtus communis) as a 2:1 mixture of two rotamers. The known trimeric phloroglucinol myrtucommulone A (1) was also isolated and characterized spectroscopically as a silylated cyclized derivative (5). Myrtucommulone A showed significant antibacterial activity against multidrug-resistant (MDR) clinically relevant bacteria, while semimyrtucommulone was less active.

引用

页码：334 / 338

页数：5

共 24 条

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