Nucleotide sequence, chromosome localization, and evolutionary conservation of a serine hydroxymethyltransferase-processed pseudogene

被引：5

作者：

Devor, EJ

DillDevor, RM

机构：

[1] Department of Psychiatry, University of Iowa College of Medicine, Iowa City, IA

来源：

HUMAN HEREDITY | 1997年 / 47卷 / 03期

关键词：

SHMT; cloning; sequencing; evolutionary; conservation; human;

D O I：

10.1159/000154400

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The nucleotide sequence and chromosomal localization of a human pseudogene is reported. Sequence data suggest that this pseudogene was derived via reverse transcription from the gene encoding the cytosolic isoform of the enzyme serine hydroxymethyltransferase. In addition, a heteroduplex analysis of this pseudogene among several species of nonhuman primate indicates a relatively high degree of sequence conservation.

引用

页码：125 / 130

页数：6

共 14 条

[1] NUCLEOTIDE-SEQUENCE AND EXPRESSION OF A CDNA-ENCODING RABBIT LIVER CYTOSOLIC SERINE HYDROXYMETHYLTRANSFERASE [J].