Opening chromatin

被引:23
作者
Lomvardas, S [1 ]
Thanos, D [1 ]
机构
[1] Columbia Univ, Dept Biochem & Mol Biophys, New York, NY 10032 USA
关键词
D O I
10.1016/S1097-2765(02)00463-X
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
How the transcriptional apparatus gains access to and subsequently opens compacted chromatin has remained a mystery. Now in this issue of Molecular Cell, Zaret and coworkers show that chromatin opening in vitro is not mediated by the classical chromatin remodeling machines but instead occurs through specific transcription factor-histone interactions.
引用
收藏
页码:209 / 211
页数:3
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