Vitamin D: a D-Lightful health perspective

被引:242
作者
Holick, Michael F. [1 ]
机构
[1] Boston Univ, Sch Med,Bone Res Lab, Med Ctr, Dept Med,Sect Endocrinol Nutr & Diabet Vitamin D, Boston, MA 02118 USA
关键词
25-hydroxyvitamin D; cancer; cardiovascular disease; sunlight; vitamin D;
D O I
10.1111/j.1753-4887.2008.00104.x
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Sunlight provides most humans with their vitamin D requirement. Adequate vitamin D-3 by synthesis in the skin or from dietary and supplemental sources is essential for bone health throughout life. Vitamin D deficiency is defined as a 25(OH)D concentration < 20 ng/mL (50 nmol/L); vitamin D sufficiency as a 25(OH)D > 30 ng/mL (75 nmol/L), and insufficiency as 21-29 ng/mL. Vitamin D deficiency and insufficiency has been linked to a wide variety of chronic diseases including common cancers, autoimmune, cardiovascular, and infectious diseases. Healthcare professionals need to be aware of the vitamin D deficiency pandemic. Guidelines for sensible sun exposure and supplemental vitamin D of 800-1000 IU/day are needed. (C) 2008 International Life Sciences Institute.
引用
收藏
页码:S182 / S194
页数:13
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