Xerostomia and the geriatric patient

被引:229
作者
Ship, JA
Pillemer, SR
Baum, BJ
机构
[1] NYU, Coll Dent, Dept Oral Med, New York, NY 10010 USA
[2] NYU, Coll Dent, Bluestone Ctr Clin Res, New York, NY 10010 USA
[3] Natl Inst Dent & Craniofacial Res, Gene Therapy & Therapeut Branch, NIH, Bethesda, MD USA
关键词
xerostomia; aging; saliva; Sjogren's; cancer; radiotherapy; medications;
D O I
10.1046/j.1532-5415.2002.50123.x
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Saliva is essential for the preservation of oral-pharyngeal health, and disorders of salivary physiology are associated with numerous oral and pharyngeal problems, particularly in older people. Although salivary function is remarkably intact in healthy aging, medical problems, medications, and head and neck radiotherapy can cause salivary dysfunction and complaints of xerostomia among older people. Sjogren's syndrome, an autoimmune exocrinopathy, is the most common medical disease associated with salivary dysfunction. Medications with anticholinergic side effects will impair salivary output, and head and neck radiotherapy for cancer will cause permanent destruction of salivary glands. Treatments for salivary problems are based upon establishing a diagnosis, protecting oral and pharyngeal health, stimulating remaining glands, and replacing lost salivary fluids.
引用
收藏
页码:535 / 543
页数:9
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